Papilloma refers to a benign epithelialtumor growing exophytically (outwardly projecting) in finger-like fronds. In this context papilla refers to the projection created by the tumor, not a tumor on an already existing papilla (such as the nipple). When used without context, it commonly refers to infections caused by human papillomavirus (HPV), such as warts. There are, however, a number of other conditions that cause papilloma, such as choroid plexus papilloma (CPP) and pearly penile papules of the penis.
Human Papilloma Virus infection is a major cause of cervical cancer, although most HPV infections do not cause cancer.